Silagra 50 mg is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate as its active ingredient, and its mechanism of action is similar to other medications in the same class. Sexual stimulation leads to the release of nitric oxide (NO) in the erectile tissue of the penis. Nitric oxide activates an enzyme called guanylate cyclase, which results in an increase in cyclic guanosine monophosphate (cGMP).